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Diagnostic Cytology Seminar 2020
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The Diagnostic Cytology Seminar 2020 features slides and case histories for some challenging and interesting cases. This is your chance to make a thought-provoking diagnoses.  The results will be compiled and presented during this Seminar. Everyone is encouraged to participate in this online activity, even if you are unable to attend the meeting. All responses will be anonymous. You can participate individually or as a group and make it a fun experience for all. The final diagnosis will be posted on the website after the Annual Meeting.



Jennifer Brainard, MD

Melissa L. Randolph, BS, SCT(ASCP)


Longwen Chen, MD, PhD

Juan Xing, MD

Mariana Canepa, MD

Christa Swisher, BS, CT(ASCP)


Submit your diagnoses by October 25, 2020.

If viewing on a mobile device, scroll over to see all cases.



 Case 1

Clinical History

A 47 year old man with chronic back pain presented to the Emergency Department with worsening back pain and new onset abdominal pain. A CT scan showed multiple liver, spleen, lung and bone lesions as well as hilar and mediastinal adenopathy. An EBUS-guided FNA of an 11L lymph node was performed.


 Case 2

Clinical History

An 82 year old man presented with a 6 month history of fatigue and weight loss. The patient is a former smoker with asbestos exposure. A chest CT showed a large right hilar mass which is mildly PET avid. An EBUS-guided FNA of the right hilar mass was performed.


Case 3

Clinical History

A 74 year old man with history of severe coronary artery disease status post CABG and diabetes presented to his primary care physician with right upper extremity swelling. He was referred for CT angiography which showed an anterior mediastinal mass with a suspected thrombus in the superior vena cava. A transesophageal echo showed a mediastinal mass with extension to the right atrium and superior vena cava. A touch preparation and biopsy of the superior vena cava mass was performed.


 Case 4

Clinical History

A 72 year old woman with history of diabetes presented to the Emergency Department with left leg swelling and numbness. A venous Doppler showed extensive left leg deep venous thrombosis (DVT). A CT scan of the chest to rule out a pulmonary embolism revealed a 4cm right paratracheal mass. An EBUS-guided FNA of the right paratracheal mass was performed.



Case 5

Clinical History

A 63- year-old woman that has experienced post-menopausal bleeding for a period of 7 months. Pap Test, Cervical/Endocervical, however, Cervix could not be visualized.




 Case 6

Clinical History

A 56 year old man with history of papillary thyroid carcinoma presented to his ophthalmologist with a one year history of blurred vision and a one month history of a dark spot in his right eye. A multi pigmented right choroidal mass was seen on exam associated with subretinal hemorrhage. The patient was referred to ocular oncology. An FNA of the choroidal mass was performed. 



Case 7

Clinical History

A 46 year old male former smoker presented with exertional dyspnea and cough.  A chest x-ray showed a right hilar fullness. A CT scan showed a large soft tissue attenuation mass in the mediastinum and right hilum. An EBUS-guided FNA of the mass was performed.


 Case 8

Clinical History

A 48 year old male with MEN I and a history of hyper-parathyroidism.  2.4 cm Left Pleural Based Mass



Three random winners, from among the bonus case correct answers, will recieve a 
$50.00 Amazon gift card!


Bonus Case 9

Clinical History

The patient is an 82 year old woman with a history of nasopharyngeal carcinoma with a new right lower lobe lung nodule. Aspirate of the right lower lobe nodule.



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